Mechanical shearing simulations on selected structures illustrate that the nanoscale behaviour of silk protein assemblies is controlled by the 

Generally, spider silk is a highly ordered protein fiber spun by spiders. In-depth understanding of natural structuring and synthesis highlights 

The reports on base sequences of spider silk protein genes have gained importance as the mechanical properties of silk fibers have been revealed.

In this study, we designed a circularized mRNA (cmRNA) employing the RNA cyclase ribozyme mechanism. cmRNAs encoding spider silk protein MaSp1 and FSLP were designed based on only one unit of the template sequence but provide ribosomes with a circular and infinite translation template for production of long peptides containing tandem repeats

Fermenting fabrics Spiders create webs by spinning liquid protein into silk. Although silkworms have been bred to produce silk for thousands of years, spiders are cannibals which makes them

Protein secondary structure is probably the aspect of spider silk structure most challenging to determine. Experiments studying entire spider silk fibers have suggested that they are a

Spider dragline silk is a remarkable fiber made of unique proteins—spidroins—secreted and stored as a concentrated aqueous dope in the major ampullate gland of 

In early studies, proteins containing long tandem repeats, such as major ampullate spidroin 1 (MaSp1) and flagelliform silk protein (FSLP), were 

Here, we reviewed the application of recombinant spider silk protein eADF4(C16), major ampullate spidroin (MaSp), minor ampullate spidroin (MiSp), and the 

Spider silk primarily consists of proteins that possess large quantities of nonpolar and hydrophobic amino acids like glycine or alanine, but for example, no or only very little tryptophan. In comparison to common cellular enzymes, it is evident that silk proteins exhibit a quite aberrant amino acid composition (Fig.

The engineered spider silk protein eADF4(C16) reveals similarities to amphiphilic block copolymers. Drop cast of protein solutions on different hydrophobic